Figure 1: Neuroblastoma, poorly differentiated; (a) Contrast-enhanced CT—a posterior mediastinal mass encroaching paravertebral region (yellow arrow); (b) Neuroblasts with rosettes and neuropil (H and E, 40X); (c) Bone marrow biopsy—diffuse infiltration by malignant small round cells (H and E, 4X); (d) Lymph node metastasis (H and E, 20X); (e) CD45 expression in lymphocytes while the metastatic focus is negative (IHC, 20X); (f) Metastatic focus in node shows synaptophysin expression (IHC, 20X); CT—Computed tomography; H and E—Hematoxylin and eosin; IHC—Immunohistochemistry; CD—Cluster of differentiation