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  Indian J Med Microbiol
 

Figure 2: 100× view: In an interphase nucleus lacking a translocation involving the 8q24.21 band, two orange/green fusion signals are expected representing two normal (non-rearranged) 8q24.21 loci. A signal pattern consisting of one orange/green fusion signal, one orange signal, and a separate green signal indicates one normal 8q24.21 locus and one 8q24.21 locus affected by an 8q24.21 translocation. Alternating breakpoints observed in variant MYC translocations t(8;22) and t(2;8) might result in different signal patterns

Figure 2: 100× view: In an interphase nucleus lacking a translocation involving the 8q24.21 band, two orange/green fusion signals are expected representing two normal (non-rearranged) 8q24.21 loci. A signal pattern consisting of one orange/green fusion signal, one orange signal, and a separate green signal indicates one normal 8q24.21 locus and one 8q24.21 locus affected by an 8q24.21 translocation. Alternating breakpoints observed in variant MYC translocations t(8;22) and t(2;8) might result in different signal patterns