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  Indian J Med Microbiol
 

Figure 3: Representative tumor sections on IHC shows (4x, 10x, 40x) (a) PB subtype: CK 7, MUC1, MUC5ac cytoplasmic positivity; CK 20, MUC2, CDX2, CA 19.9 is negative; and Ki-67 proliferative index of 40-50% in tumor cells. (b) Intestinal subtype: CK7, CK20, MUC 2, CA 19.9 cytoplasmic positive and CDX2 is nuclear positive, MUC 1, MUC5ac is negative, Ki-67 proliferative index is 30% in tumor cells (c) Mixed subtype: CK7, MUC1, CK20, MUC5ac, CA-19.9 is focal cytoplasmic positive and CDX2 is nuclear positivity, MUC2 is negative, and Ki-67 shows a proliferative index of 50-60% in tumor cells

Figure 3: Representative tumor sections on IHC shows (4x, 10x, 40x) (a) PB subtype: CK 7, MUC1, MUC5ac cytoplasmic positivity; CK 20, MUC2, CDX2, CA 19.9 is negative; and Ki-67 proliferative index of 40-50% in tumor cells. (b) Intestinal subtype: CK7, CK20, MUC 2, CA 19.9 cytoplasmic positive and CDX2 is nuclear positive, MUC 1, MUC5ac is negative, Ki-67 proliferative index is 30% in tumor cells (c) Mixed subtype: CK7, MUC1, CK20, MUC5ac, CA-19.9 is focal cytoplasmic positive and CDX2 is nuclear positivity, MUC2 is negative, and Ki-67 shows a proliferative index of 50-60% in tumor cells