Figure 1: a-d: Tumor budding in invasive breast carcinoma. (a) Tissue section of invasive carcinoma of no special type displaying no tumor buds at the invasive front of the tumor. (H and E, X400). (b) Tissue section of invasive carcinoma of no special type displaying three tumor buds (Black arrows) at the invasive front of the tumor. (H and E, X400). (c) Tissue section of invasive carcinoma of no special type displaying a single tumor bud (Black arrow) at the invasive front of the tumor. (H and E, X400). (d) Tissue section of invasive mucinous carcinoma with neuroendocrine differentiation displaying a single tumor bud (black arrow) at the invasive front of the tumor. (H and E, X400)