Figure 1: The pathways controlled by the Axl receptor; Dimerization and activation of Axl receptor by binding of Gas 6 molecule provides proliferation via Ras/Raf/ERK1 / 2 pathway, survival, and migration via PI3K pathway. Axl induces epithelial-mesenchymal transformation (EMT) by attaching a phosphate group to different regions of Smad3 via JNK[24,25] Abbreviations: JNK: c-Jun N-terminal kinase, SMAD: mothers against decapentaplegic homolog
![Figure 1: The pathways controlled by the Axl receptor; Dimerization and activation of Axl receptor by binding of Gas 6 molecule provides proliferation via Ras/Raf/ERK1 / 2 pathway, survival, and migration via PI3K pathway. Axl induces epithelial-mesenchymal transformation (EMT) by attaching a phosphate group to different regions of Smad3 via JNK[24,25] Abbreviations: JNK: c-Jun N-terminal kinase, SMAD: mothers against decapentaplegic homolog](articles/0/0/0/images/IndianJPatholMicrobiol_0_0_0_0_367698_f1.jpg)