Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Reader Login
Users Online: 2877
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
Export selected to
Reference Manager
Medlars Format
RefWorks Format
BibTex Format
  Citation statistics : Table of Contents
   2001| April  | Volume 44 | Issue 2  
    Online since October 12, 2009

  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
Hide all abstracts  Show selected abstracts  Export selected to
  Cited Viewed PDF
Polymerase chain reaction using IS6110 primer to detect Mycobacterium tuberculosis in clinical samples.
P Gunisha, H N Madhavan, U Jayanthi, K L Therese
April 2001, 44(2):97-102
Nucleic acid amplification using IS6110 primers to detect Mycobacterium tuberculosis in clinical specimens has been extensively used as laboratory tool for the diagnosis for tuberculosis. Despite it's dramatic scientific value in practice, it is not as sensitive as expected for the detection of M. tuberculosis. The results of the study suggest that PCR using 123 bp fragment of DNA belonging to IS6110 is specific (95.6%) but only has a sensitivity of 30% to detect M. tuberculosis in clinical specimens.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  8 816 287
Prevalence of bacterial vaginosis in antenatal women.
R Mathew, J Kalyani, R Bibi, M Mallika
April 2001, 44(2):113-6
Bacterial vaginosis is an established risk factor in pregnant women for premature rupture of membranes and preterm delivery. This study was carried out to find out the prevalence of Bacterial Vaginosis (BV) in antenatal women with vaginal discharge and the effect of treatment with Metronidazole gel on pregnancy outcome. One hundred and fifty symptomatic and fifty asymptomatic women in second trimester of pregnancy in the age group of 20-30 years were included in the study. Gram stained smears of vaginal discharge were examined for evidence of BV with a scoring system by Nugent et al and was found to be positive in 38.5% in symptomatic antenatal women. Intravaginal metronidazole gel application was found to be an effective therapeutic option. Incidence of preterm labour was more in untreated cases.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  7 907 219
Leiomyosarcoma arising from tunica vaginalis testis : a case report.
P Bajaj, K Agarwal, S R Niveditha, O P Pathania
April 2001, 44(2):145-6
Benign and malignant soft tissue tumors of the paratesticular region i.e. those arising from the testicular tunics, epididymis and spermatic cord are uncommon. Of these, leiomyosarcoma arising from the tunica vaginalis is extremely rare. On extensive computerised search, a single case has been reported till date in the literature. We hereby report one such case because of its rarity.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  5 699 77
Amyloid goiter--a case report.
H C Kapadia, R I Desai, I M Desai, N R Parikh
April 2001, 44(2):147-8
Microscopic infiltration of the thyroid gland by amyloid is an uncommon but well recognized phenomenon and significant enlargement of the thyroid due to deposition of amyloid is rarely seen. This condition has to be distinguished from other types of goiters and at times from malignancy. In spite of extensive involvement of the gland by amyloid, thyroid function usually remains normal. Here, we describe a rare case of amyloid goiter without amyloid deposits in any other organs of the body. The case presented in an unusual clinical settings of relatively rapid enlargement of thyroid with pressure symptoms and was unassociated with any immuno-proliferative or chronic diseases.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  5 727 97
Study of anticardiolipin antibodies in repeated abortions--an institutional experience.
J J Sheth, F J Sheth
April 2001, 44(2):117-21
A cohort of 178 pregnant women with a history of first or second trimester abortions (2 or more) were the base of present study. In all, other causes of abortion were ruled out except for anti-phospholipid syndrome. Anti-Cardiolipin antibody (ACA) (IgG & IgM) was estimated in the sera samples of all women. Out of 178 women, any one or both immunoglobulins were above the cut off range (> 15.0 units) in 47 (26.4%) while both immunoglobulins were normal in 131 (73.59%) women. Both immunoglobulins were present in only 0.5% women. ACA-IgG alone was present in 11.79% while ACA-IgM alone was present in 14.04% women. We observe from present study that ACA is a major cause of recurrent fetal loss & many pregnancies can be saved if diagnosed & treated adequately.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  4 775 105
Bacterial indices of drinking water from natural sources.
K Thakur, P S Grover
April 2001, 44(2):131-4
Two hundred forty samples of water from twenty natural sources were subjected to the study for the detection of four bacterial indicators of faecal pollution. The samples were subjected to the detection of coliform, faecal coliform, E. coli, S. faecalis, Cl. welchii and plate count at 37 degrees C and 22 degrees C. All these samples were found unfit for human consumption. MPN for coliforms, E. coli and S. faecalis varied from 3 to 1800 per 100 ml of water, sero to 1800 per 100 ml water and zero to 540 per 100 ml of water respectively. Plate count at 37 degrees C and 22 degrees C varied from 2.5 x 10(3) to > 150 x 10(3) per ml of water. Cl. welchii was detected in 30.4% samples in rainy season and high plate count at 37 degrees C and 22 degrees C was observed during the same period.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  4 797 133
Immunohistochemical localization of transferrin in human breast cancer tissue.
P K Agarwal, A Mehrotra, T Chandra, K Singh
April 2001, 44(2):107-11
The present study was planned to detect the iron binding protein, transferrin (TR) in paraffin sections of the human breast tumors. The distribution of transferrin has been studied in 153 cases (63 benign lesions and 90 malignant tumors). The extent of staining reaction was determined by semiquantitative grading (weak, moderate and consistent). Positivity rate for transferrin was higher (92.2%) in malignant tumors as compared to benign breast lesions (28.5%) with significant p value (P = .0001) for both the groups. The intensity was variable in both the groups, being more intense in the malignant tumors. Tumors with higher grade of malignancy presented consistent positive staining along with the lymph nodes involved. The extent of immunoreactivity revealed a significant positive correlation with axillary lymph node status. However, no significant correlation was found with the age of the patients. Thus the study of transferrin in breast tumors besides being of prognostic significance helps in the further management of malignant lesions of the breast.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  3 750 70
Malignant peritoneal mesothelioma deciduoid or anaplastic variant? Point to ponder.
S Desai, S Kane, S Bharde, J N Kulkarni, C S Soman
April 2001, 44(2):159-62
A case of peritoneal mesothelioma displaying unusual morphology, occurring in a 53 year old woman is described. The role of immunohistochemistry and electron microscopy in the evaluation of this tumor is stressed. The appropriate terminology to be used and possible etiologic factor are also discussed.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  3 880 79
Nerve cell markers in ossifying fibromyxoid tumour of soft parts.
T Shet, S Desai, S Kane, I Vora
April 2001, 44(2):163-7
Reported herein are two benign ossifying fibromyxoid tumors (OFMTs) of the soft tissues in axilla and terminal phalanx respectively. Both cases on immunohistochemistry (IHC) showed reactivity for vimentin, S-100 protein and glial fibrillary acidic protein (GFAP) antibodies. In addition, a focal/diffuse strong positivity for neurofilament (NF) and neuron specific enolase (NSE) was observed. Electron microscopy in one instance revealed abundant intermediate filaments, primitive cell junctions and a focally present external lamina. In the light of nerve cell differentiation of these tumors and the similarity of IHC profile and EM features of OFMT to a poorly differentiated malignant peripheral nerve sheath tumor (MPNST); it is suggested that OFMT is a variably differentiated PNST rather than a simple Schwannian neoplasm as is believed.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  3 743 86
Fine needle aspiration cytology, histology and MIB-1 proliferative index in a case of dyshormonogenetic goitre.
A K Karak, M Sahoo, D Bhatnagar
April 2001, 44(2):169-72
The fine needle aspiration (FNA) cytologic findings along with histology and MIB-1 proliferative index in a case of dyshormonogenetic goitre is presented. A 12-year old female child from non-endemic zone presented with a isotopically cold solitary thyroid nodule with a history of goitre being present since birth. Past history of any neck irradiation or maternal ingestion of any goitrogen during the antenatal period and family history of goitre were negative. FNA cytology revealed an extremely cellular preparation with predominantly microfollicular pattern without colloid. Nuclei were round to oval, slightly enlarged with evenly distributed chromatin and inconspicuous nucleoli. Larger tissue fragments also showed foci of solid cell groups with nuclear crowding, overlapping and loss of polarity in addition to the prevalent microfollicular pattern. Occasional tissue fragments showed solid groups of trapped follicular epithelial cells in the matrix of fibrocollagenous tissue. Histology showed an intensely hyperplastic follicular cells with nodule formation, irregular fibrosis, pseudo capsular or vascular wall invasion mimicking malignancy. Immunohistochemistry for calcitonin was negative but thyroglobulin was positive. MIB-1 (Ki-67) proliferation index varied from 0.05 to 0.26 (mean 0.13) in the hyperplastic nodules versus 0.9 to 2.1 (mean 1.34) in the hyperplastic solid microfoci scattered amidst the grossly normal appearing thyroid tissue. The possible cytologic diagnostic pitfalls in favor of follicular neoplasm is discussed.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  2 894 99
Ovarian granulosa cell 'tumorlet' and mature follicles with ectopic decidua in pregnancy--a case report.
S Satyanarayana, J K Bohre
April 2001, 44(2):149-50
Non-neoplastic, tumor like lesions are encountered in the ovaries during pregnancy. Of these pregnancy luteoma is the most common lesion mimicking an ovarian neoplasm. Ovarian granulosa cell proliferations are also reported in the ovaries removed during pregnancy as an incidental finding. The granulosa cell proliferation occurs due to the follicular stimulating hormone (FSH) like activity of human chorionic gonadotropin (hCG). We report a case of second gravida who developed uterine atonia, necessitating emergency hysterectomy. Right ovary showed extensive ectopic decidua, numerous well-formed follicles and granulosa cell tumor-like proliferation. Usually follicles are not formed in the ovaries during pregnancy. The same FSH like activity of hCG might have been responsible for the formation and maturation of follicles in this case.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  2 718 80
Rapid diagnosis of cholera by coagglutination test.
A R Hanumanthappa, V Rajagopal
April 2001, 44(2):123-4
In this study the coagglutination test for the rapid diagnosis of cholera is evaluated in comparison with the conventional culture method. A total of 553 stool specimens were processed from cases of acute gastro-enteritis. The sensitivity and specificity of coagglutination test was 92.77% and 95.65% respectively. The coagglutination test is found to be simple, reliable and rapid method for the diagnosis of cholera.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  2 620 86
Sclerosing mediastinitis caused by Aspergillus terreus.
S Verghese, T Methew, P Padmaja, A Mullasari, A Sivaraman, V M Kurien
April 2001, 44(2):141-3
A case of Aspergillus terreus causing sclerosing mediastinitis which presented with symptoms of cardiorespiratory compromise and compressive myelopathy is described. The diagnosis was established by culturing and isolating the fungus in pure culture from the tissue and was also confirmed by demonstration of sepcific precipitating antibodies against Aspergillus terreus in patient's serum.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  2 717 76
Omental cyst in children presenting as pseudoascites : report of two cases and review of the literature.
K K Prasad, M Jain, R K Gupta
April 2001, 44(2):153-5
An omental cyst is a rare intra-abdominal lesion. Absence of characteristic clinical findings make the diagnosis difficult. These cases are reported because of its rarity. The brief review of the features of omental cyst is included in order to increase awareness of this entity.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  2 825 119
Emergence of Vibrio cholerae 0139 in Manipal-coastal Karnataka-South India.
M Ballal, B Nandanan, P G Shivananda
April 2001, 44(2):177-177
Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 358 51
Infective complications of central venous catheters in cardiac surgical patients.
B Dhawan, R Chaudhry, M Hote, A Bhan, P Venugopal
April 2001, 44(2):125-9
Prospective randomised study was conducted over a 24 months period in a cardiac surgical intensive care unit to determine the incidence of infection associated with multilumen venous catheters. The influence of various factors including fever, peripheral blood culture, catheter site, catheter usage for monitoring central venous pressure and/inotrope therapy on infection rates were statistically evaluated. A total of 100 catheters submitted to the Microbiology laboratory were bacteriologically examined. Forty-nine of these were inserted into upper body sites, and 51 were inserted into the femoral vein. Twenty-one were triple-lumen catheters. Catheters were removed when a central line was no longer necessary. Catheter tips were cultured by semiquantitative technique for aerobic and anaerobic bacteria. Bacteremia occurred in 3% of catheter insertions; (Enterococcus faecalis, one; Enterobacter spp. One; Acinetobacter spp., one); and catheter colonisation developed in 24%. Neither catheter colonisation nor catheter related infection were associated with any of the risk factors evaluated. Our data indicates that central venous catheters are safe to use in our patients. The inability to identify "risk factors" for catheter infection emphasise the need to maintain a high index of suspicion.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 825 106
Fine needle aspiration biopsy of ovarian neoplasm.
P Dey, S C Saha, K K Dhar
April 2001, 44(2):103-6
Twenty cases of ovarian neoplasm (12 non-coelomic and 8 coelomic and 8 epithelial tumors) have been subjected to fine needle aspiration biopsy (FNAB). FNAB yielded adequate material in all those cases and it was possible to accurately classify the tumors in 16 cases (80%). In eight cases of non coelomic epithelial neoplasms preoperative cytological diagnosis helped in conservative surgery. Cytological features of different groups of ovarian tumors are to some extent characteristic. FNAB is a relatively safe and reliable diagnostic procedure.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 719 87
Recurrent infantile digital fibromatosis--a rare entity.
N Khan, K Alam, V Maheshwari, A H Khan
April 2001, 44(2):135-6
We present here a rare case of Infantile Digital Fibromatosis in a six year old female child who presented with recurrent swelling over the phalanx of left middle finger.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 648 59
Cytodiagnosis of retroperitoneal primitive neuroectodermal tumour (PNET)--a case report.
M I Kale, A K Rao, Y R Patwardhan
April 2001, 44(2):137-9
A rare case of Retroperitoneal Primitive Neuro Ectodermal Tumour (PNET) in thirty years old female is presented. Fine needle aspiration cytology (FNAC) characterised by small round cells with scanty cytoplasm, poorly to well formed rosettes with neurofibrillary background; whereas periodic acid-schiff (PAS) rarely react with Primitive Neuro Ectodermal Tumour (PNET), prompted the diagnosis of PNET at cytology itself. Cytological appearances of PNET have been reviewed and the various differential diagnoses are discussed.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 727 89
Pseudomyxoma peritonei of hernial sac--a case report.
T S Jaswal, S Singh, R Agarwal, M Singh, H L Khatri, B Arora
April 2001, 44(2):151-2
A rare presentation of Pseudomyxoma Peritonei of hernial sac is described. The patient was admitted for repair of an inguinal hernia. During herniorraphy large amount of mucinous material was found in hernial sac. Microscopy revealed epithelial glandular cells with bland appearance within mucinous pools. A search for primary remained fruitless.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]  [PubMed]
  1 742 72
Primary malignant giant cell tumour of sacrum--a case report.
R Mahajan, U Sharma, V H Talib
April 2001, 44(2):173-5
A rare case of primary malignant GCT of sacrum in a 35-year-old female is reported.
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  - 708 73
Accuracy : key word in quality control in clinical chemistry.
S K Shali, S Ranga
April 2001, 44(2):95-6
Full text not available  [PDF]  [PubMed]
  - 381 52
Acute lymphoblastic leukaemia with giant intracytoplasmic inclusion--a case report.
S Sharma, S Narayan, M Kaur
April 2001, 44(2):157-8
Acute Lymphoblastic Leukaemia (ALL) with intracytoplasmic inclusions is a rare and unusual subtype of acute leukaemia. Here we describe a case of ALL with intracytoplasmic inclusions in an adult female. These inclusions stained negative for Myeloperoxidase (MPO), Sudan Black B (SBB) and Alpha-naphthyl acetate estarase (ANAE) and positive for Periodic Acid Schiff (PAS). This case is being presented for its unusual occurrence and to recognise the characteristics of this subtype of ALL to avoid a misdiagnosis of AML (Acute Myeloid Leukaemia).
[ABSTRACT]   Full text not available  [PDF]  [PubMed]
  - 695 69
  The Journal 
  Site Statistics 
  My Preferences 
  Online Submission 
  Editorial Board