Indian Journal of Pathology and Microbiology

EDITORIAL
Year
: 2023  |  Volume : 66  |  Issue : 3  |  Page : 443-

From the Editor's desk


Bharat Rekhi 
 MD, DNB, MIAC, FICP, MCAP(Affl.), FRC-Path, Professor/Pathologist, Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Bharat Rekhi
MD, DNB, MIAC, FICP, MCAP(Affl.), FRC-Path, Professor/Pathologist, Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India
India




How to cite this article:
Rekhi B. From the Editor's desk.Indian J Pathol Microbiol 2023;66:443-443


How to cite this URL:
Rekhi B. From the Editor's desk. Indian J Pathol Microbiol [serial online] 2023 [cited 2023 Sep 30 ];66:443-443
Available from: https://www.ijpmonline.org/text.asp?2023/66/3/443/382465


Full Text



Dear Readers,

I am happy to inform you that the impact factor of our journal has escalated to 1.0. This is a result of the collaborative efforts of all the earlier editors, associate and assistant editors; the active editorial members, reviewers, authors, and the technical support team. I look forward to this continuing support for further enhancement of the impact of our journal.

This issue features original research spanning from the value of time-honored histopathological parameters, to the addition of newer markers for prognostication and prediction; value addition of techniques, such as next-generation sequencing (NGS), for unraveling mutations involved in the pathogenesis of certain aggressive tumors that could probably be targeted for a therapeutic benefit and the potential of stem cell markers as a guide to neoadjuvant therapy in certain carcinomas.

Fonseca et al.[1] have demonstrated the prognostic and predictive value of certain routine histomorphological parameters, including the Brandwein–Gensler risk model in early-stage oral squamous cell carcinomas.

Erdogan et al.[2] observed certain underlying mutations in uterine carcinosarcomas using NGS that could provide additional insights toward potential targeted therapies for these relatively aggressive tumors.

Bedeer et al.[3] noted that increased expression of chemokine receptor type 4 (CXCR4) and decreased expression of peroxisome proliferator activator-gamma (PPAR-γ) are associated with increased grade, advanced stage, and vascular invasion in colorectal carcinomas.

In their study, Mohamedali et al.[4] observed that a strong expression of EZH2 and weak expression of H3K27me3 are associated with high grade, increased proliferation, and invasive behavior in cases of urothelial carcinomas.

Gucin et al.[5] have shown a possible role of certain stem cell markers as a guide to neoadjuvant chemotherapy in breast carcinomas.

I hope you all feel enriched with the scientific content of this issue and we continue receiving more of high-quality research, especially original and review articles.

References

1Fonseca D, Khemani R, Pasam MK, Tagore R, Rao BV, Kodandapani S, et al. Histological risk score and its role in predicting recurrence in early-stage oral squamous cell carcinomas. Indian J Pathol Microbiol 2023;66:444-8.
2Erdoğan EG, Yalta TD, Can N, Süt N, Taştekin E, Usta U, et al. Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience. Indian J Pathol Microbiol 2023;66:449-55.
3Bedeer AE, Heabah NA. Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-γ) expression in colorectal carcinoma: Relation to the available clinicopathological parameters. Indian J Pathol Microbiol 2023;66:465-471.
4Mohamedali R, Mitra S, Mandal S, Nayak P, Adhya AK, Purkait S. Expression of EZH2 and H3K27me3 predicts tumor biology of urothelial carcinoma. Indian J Pathol Microbiol 2023;66:488-494.
5Gucin Z, Buyukpinarbasili N, Gecer MO, Ersoy YE, Turk HM, Yildiz S, et al. Stem cell markers: A guıde to neoadjuvant therapy ın breast carcinomas. Indian J Pathol Microbiol 2023;66:495-501.