Year : 2023 | Volume
: 66 | Issue : 1 | Page : 1--2
Towards a value-based research by building bridges and collaboration
MD, DNB, MIAC, FICP, MCAP(Affl.), FRC-Path, Professor/Pathologist, Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India
MD, DNB, MIAC, FICP, MCAP(Affl.), FRC-Path, Professor/Pathologist, Department of Surgical Pathology, Tata Memorial Hospital, Mumbai, Maharashtra
|How to cite this article:|
Rekhi B. Towards a value-based research by building bridges and collaboration.Indian J Pathol Microbiol 2023;66:1-2
|How to cite this URL:|
Rekhi B. Towards a value-based research by building bridges and collaboration. Indian J Pathol Microbiol [serial online] 2023 [cited 2023 Mar 27 ];66:1-2
Available from: https://www.ijpmonline.org/text.asp?2023/66/1/1/368005
Wishing you all a Very Happy New Year, 2023. I feel honored and privileged to be elected as the new Editor-In-Chief of the prestigious Indian Journal of Pathology and Microbiology.
I would begin with the following quotation from Charles Darwin:
“In the long history of humankind (and animal kind, too) those who learned to collaborate and improvise most effectively have prevailed.”
Pathology and microbiology constitute one of the finest examples of medicine that bridge basic science and clinical care. We have witnessed this over the years and during the COVID-19 pandemic when various branches of medical science joined for a common cause to defeat the virus. This also led to an upsurge in the submissions of manuscripts, focussing on various aspects of COVID-19. Pathologists form an essential pillar of multidisciplinary care in modern medicine, including evidence-based, personalized, and precision medicine.
Collaboration can lead to the generation of data with a wider perspective. Collaboration of a pathologist can be with the radiologist, basic scientist, microbiologist, surgeon, or medical physician, with other pathologists from different institutions, and even with scientists from other disciplines, as per a study design and regulations. Collaboration in the form of multidisciplinary groups enhances patient care and within a research group can lead to building a robust database or formulation of guidelines. High-quality data, based on collaborative efforts or the formulation of guidelines can lead to a substantial publication that would contribute to patient care at large.
Although diagnosing a single patient and treating the same can influence a single precious life, quality research can form a basis for influencing management across several precious lives. Diagnosis and research constitute two essential components of pathology. We stand on the shoulders of great pathologists who were excellent diagnosticians and simultaneously contributed significantly toward research in pathology.
Therefore, it would be ideal for a pathologist to be actively involved in research and service at the same time. The value of a thesis while pursuing a doctorate in pathology cannot be overemphasized. It is one of the first opportunity for a resident to understand the nuances of research, both from the scientific and ethical perspective, from his/her mentor or guide. While collaborating with one's student, the guide has an opportunity to focus on a subject that can contribute towards understanding a clinicopathological spectrum of a disease, unraveling disease pathways, identifying or validating newer molecules, and further towards patient management. Value-based research by far would be scientifically and ethically sound. A high-quality research manuscript, published in a peer-reviewed journal, is reflective of an investigator's performance. Promotion of excellence in research will lead to an improved or more value-based system including in pathology.
The first issue of IJPM in the new year contains articles that reflect various interesting aspects of pathology and microbiology, including the importance of time-honored morphological features to the value addition of immunohistochemical markers as diagnostic, prognostic, and predictive adjuncts, along with importance of molecular pathology. Additionally, there are descriptions of pathological features related to certain microorganisms.
In two different studies, Yadav et al. and Argon et al. have demonstrated the prognostic value of tumor budding in oral squamous cell carcinomas and pancreatic ductal adenocarcinomas, respectively. In a study, Chaube et al. highlight the value of identifying Kocuria kristinae as an unusual pathogen in head and neck malignancy. Zeynep et al. report a significant correlation between the immunohistochemical expression of programmed death ligand-1 (PD-L1) and medullary morphology in colorectal cancer.
Pencheva et al. have described histomorphological, immunohistochemical, and molecular features, including increased Angiotensin-converting enzyme 2 (ACE 2) expression in the lungs in a series of autopsies of patients, who died of COVID-19 infection. Sayar et al. report the prognostic value of CXCL13 with its positive staining in an increased number of lymphocytes in advanced pathological stages of clear cell renal cell carcinoma. Pasricha et al. reaffirm the value addition of NKX2.2 for the diagnosing of Ewing sarcomas and further obviating or minimizing the need for FISH testing in this neoplasm.
I hope the spirit of pursuing value-based research prevails with encouragement and support in all possible ways and our journal continues to strive toward showcasing quality research in the subsequent issues and years to come.
|1||Yadav K, Singh T, Varma K, Bhargava M, Misra V. Evaluation of tumor budding and its correlation with histomorphological prognostic markers in oral squamous cell carcinoma and its association with epithelial-mesenchymal transition process. Indian J Pathol Microbiol 2023;66:3-8.|
|2||Argon A, Öz Ö, Kebat TA. Evaluation and prognostic significance of tumor budding in pancreatic ductal adenocarcinomas. Indian J Pathol Microbiol 2023;66:38-43.|
|3||Chaubey P, Mohta V, Mishra M, Wagh A, Sapre S. Kocuria kristinae-An unusual opportunistic pathogen in head and neck malignancy: Case series from central India's regional cancer care centre. Indian J Pathol Microbiol 2023;66:14-8.|
|4||Zeynep O, Funda C, Evrim Y, Deniz A, Bülent Y, Fatih YN. PD-L1 and PD-L2 expression in colorectal cancer. Indian J Pathol Microbiol 2023;66:31-7.|
|5||Pencheva MM, Genova SN. SARS-CoV-2 induced changes in the lungs based on autopsy cases. Indian J Pathol Microbiol 2023;66:19-23.|
|6||Sayar E, Yabaci A, Coban G. Can CXCL13 be a prognostic marker in clear cell renal cell carcinoma? Indian J Pathol Microbiol 2023;66:54-7.|
|7||Pasricha S, Pahwa S, Pruthi M, Jajodia A, Gupta G, Sharma A, et al. Correlation NKX2.2 IHC and EWSR1 break-apart FISH in the diagnosis of Ewing sarcoma. Can combined NKX2.2 and CD99 immunoexpression obviate or minimize the need of FISH testing? First assessment study from Indian tertiary cancer care center. Indian J Pathol Microbiol 2023;66:58-62.|