Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2021  |  Volume : 64  |  Issue : 4  |  Page : 834--836

Thigh mass in a patient with malignant pleural mesothelioma: Metastasis at an unusual site


S Sunitha, Ashini H Shah, Amisha Gami, Priti Trivedi 
 Department of Oncopathology, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India

Correspondence Address:
Ashini H Shah
Department of Oncopathology, Gujarat Cancer Research Institute, Ahmedabad, Gujarat, India. E.mail:
India

Soft tissue tumors are a highly heterogeneous group of lesions with varied clinical presentation. The majority is primary tumors and metastatic tumors are very rare. Malignant pleural mesothelioma presenting as a soft tissue mass at a distant site is even rarer and can cause diagnostic challenges both clinically and pathologically. We report a case of malignant pleural mesothelioma presenting as a soft tissue mass in the left thigh. A 59-year-old man, non-smoker, working in a cement factory since 30 years presented with complains of difficulty in walking since 1½ months. Review of his previous medical records revealed malignant pleural mesothelioma, which was diagnosed 9 months before. He had denied chemotherapy and was on Ayurvedic medication. The lesion involved the adjacent intercostal muscles. Few enlarged lymph nodes were noted in mediastinal and cervical regions. Biopsy of left supraclavicular and right cervical lymph nodes showed metastases. Metastasis from malignant pleural mesothelioma to the thigh was confirmed by immunohistochemistry. The tumor was positive for CK5/6, CK7, Calretinin and vimentin and immunonegative for CEA, Napsin A and TTF 1.


How to cite this article:
Sunitha S, Shah AH, Gami A, Trivedi P. Thigh mass in a patient with malignant pleural mesothelioma: Metastasis at an unusual site.Indian J Pathol Microbiol 2021;64:834-836


How to cite this URL:
Sunitha S, Shah AH, Gami A, Trivedi P. Thigh mass in a patient with malignant pleural mesothelioma: Metastasis at an unusual site. Indian J Pathol Microbiol [serial online] 2021 [cited 2022 Jan 27 ];64:834-836
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=4;spage=834;epage=836;aulast=Sunitha;type=0