Indian Journal of Pathology and Microbiology

BRIEF COMMUNICATION
Year
: 2019  |  Volume : 62  |  Issue : 2  |  Page : 261--265

Focal nodular hyperplasia of the liver in children: A report of 2 cases


Nelofar Islam1, Aniket Halder2, Ranajoy Ghosh2, Sugato Banerjee3, Prafulla Kumar Mishra4, Uttara Chatterjee1 
1 Department of Pathology, IPGME and R, Kolkata, West Bengal, India
2 Department of GI Pathology, IPGME and R, Kolkata, West Bengal, India
3 Department of Paediatric Surgery, KPC Medical College, Kolkata, West Bengal, India
4 Department of Paediatric Surgery, NRS Medical College, Kolkata, West Bengal, India

Correspondence Address:
Aniket Halder
No. 430/2, Ratnavilla, Nabatirtha, P.O. Hridaypur, Barasat, 24 PGS (North), Kolkata - 700 127, West Bengal
India

Focal nodular hyperplasia (FNH) is a benign non-neoplastic lesion of the liver usually found in adults. It is uncommon in children, comprising 2-10% of all pediatric liver tumours. In children, it can occur at all ages, with increased frequency between 6-10 years. We present two cases of FNH in childhood- the first being that of a 5-month-old infant, and the second in a 6-year-old boy. The possibility of congenital FNH had been excluded in the first case. The second case posed diagnostic difficulty initially and was wrongly treated for hepatoblastoma by neoadjuvant chemotherapy, but later correctly diagnosed to be FNH. Both the children are doing well on follow-up. Paediatric FNH though rare, should be kept in mind while dealing with a hepatic mass. Radiological features can be variable and needle sampling may not be sufficient to reach to a diagnosis. Histological examination with glutamine synthetase immunostaining should be performed in doubtful cases to differentiate FNH from other paediatric liver masses, as management differs.


How to cite this article:
Islam N, Halder A, Ghosh R, Banerjee S, Mishra PK, Chatterjee U. Focal nodular hyperplasia of the liver in children: A report of 2 cases.Indian J Pathol Microbiol 2019;62:261-265


How to cite this URL:
Islam N, Halder A, Ghosh R, Banerjee S, Mishra PK, Chatterjee U. Focal nodular hyperplasia of the liver in children: A report of 2 cases. Indian J Pathol Microbiol [serial online] 2019 [cited 2022 Aug 20 ];62:261-265
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=2;spage=261;epage=265;aulast=Islam;type=0