Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2015  |  Volume : 58  |  Issue : 2  |  Page : 238--240

Malignant granular cell tumor of the breast; literature review


Nalini Gupta1, Naveen Sanchety1, Pragya Saran Verma1, Geeta Verma2 
1 Department of Histopathology, Fortis Hospital, Faridabad, Haryana, India
2 Department of Histopathology, SRL, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Nalini Gupta
C6/18 Arr Dee City IInd Floor, Sector 52, Gurgoan - 122 001, Haryana
India

Malignant granular cell tumor (MGCT) is rare tumors that comprise 1-2% of all granular cell tumors. They commonly arise on lower extremity, nuchal region, chest wall, gastrointestinal tract, head, and neck but very rarely in breast. We report a case of a MGCT of breast with review of literature. The patient had noticed a breast mass 4 years back which was operated, and wide local excision was done. The tumor was diagnosed as MGCT. The tumor fulfilled 3 of the 6 criteria of Fanburg-Smith et al. The patient received 8 cycles of chemotherapy thereafter with 4 cycles of antharacycline and 4 of taxanes. However, the tumor reoccurred 4 years after resection and grew rapidly. Contrast-enhanced computed tomography done showed a large lobulated breast mass with axillary lymph node metastasis. She underwent Modified Radical Mastectomy with axillary clearance. The histopathology this time also revealed similar malignant tumor. To the best of our knowledge, only 7 cases have been reported in indexed English literature occurring primarily in breast.


How to cite this article:
Gupta N, Sanchety N, Verma PS, Verma G. Malignant granular cell tumor of the breast; literature review.Indian J Pathol Microbiol 2015;58:238-240


How to cite this URL:
Gupta N, Sanchety N, Verma PS, Verma G. Malignant granular cell tumor of the breast; literature review. Indian J Pathol Microbiol [serial online] 2015 [cited 2022 Aug 11 ];58:238-240
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=2;spage=238;epage=240;aulast=Gupta;type=0