Indian Journal of Pathology and Microbiology


Year
: 1995  |  Volume : 38  |  Issue : 4  |  Page : 393--7

Fine needle aspiration biopsy in monitoring human renal transplant.


Y M Sirpal 
 Army Hospital, Delhi Cantt, India

Correspondence Address:
Y M Sirpal
Army Hospital, Delhi Cantt, India

Renal transplant dysfunction poses a diagnostic dilemma. Clinical evaluation frequently is inaccurate and needle biopsy carries a significant risk of bleeding. Fine needle aspiration biopsy (FNAB) being an easy to perform, a less traumatic, and rapid technique, was employed in 22 cases of clinically suspected renal allograft rejection. The results were described as nil rejection, mild and severe acute rejection, chronic rejection and cyclosporin nephrotoxicity. Seven of these cases were also needle biopsied. Histology confirmed the cytology findings in all. However, an additional finding of acute vascular episode was observed in a case of chronic rejection. Fine needle aspiration biopsy diagnosis helped in altering the immunosuppressive therapy in 16 graft rejections (excluding 2 cases of irreversible rejection) and 2 cases of cyclosporin toxicity. No rejection was found in 2 cases. Thus, 20 renal grafts could be brought back to normal function. Negligible incidence of complication viz. microscopic haematuria of short duration was noted in only 1 case.


How to cite this article:
Sirpal Y. Fine needle aspiration biopsy in monitoring human renal transplant. Indian J Pathol Microbiol 1995;38:393-7


How to cite this URL:
Sirpal Y. Fine needle aspiration biopsy in monitoring human renal transplant. Indian J Pathol Microbiol [serial online] 1995 [cited 2023 Mar 23 ];38:393-7
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=1995;volume=38;issue=4;spage=393;epage=7;aulast=Sirpal;type=0