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First Isolation and Characterization of SARS-CoV-2 From COVID-19 Patient of North East India


 Indian Council of Medical Research- Regional Medical Research Centre, North East Region (ICMR-RMRCNE), Lahowal, Assam, India

Correspondence Address:
Biswajyoti Borkakoty,
Indian Council of Medical Research- Regional Medical Research Centre, North East Region (ICMR-RMRCNE), Lahowal, Dibrugarh - 786010, Assam
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpm.ijpm_748_21

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) responsible for the current pandemic has resulted in over 5 million deaths globally. More than a year has passed, still SARS-CoV-2 panic the public life. Virus isolation is of paramount importance for development of vaccines, in-vitro screening of antiviral compounds, pathogenesis studies, etc., Many cell lines were studied for amplification and replication of SARS-CoV-2 and Vero cells were found to be ideal cell lines for isolation. In May 2020, ICMR-Regional Medical Research Centre, NE region, India, successfully established the SARS-CoV-2 culture system in Vero CCL-81 cell lines. Phylogenetic analyses of the whole genome sequences of the SARS-CoV-2 isolate (EPI_ISL_2501532,2020-05-19) showed monophyletic clade G and lineage B.1.1.


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    -  Jakharia A
    -  Borkakoty B
    -  Pait S
    -  Baruah G
    -  Hazarika R
    -  Biswas D
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