Indian Journal of Pathology and Microbiology
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A novel case of left atrial and right lung mass turned out to be unconventional metastasis of uterine leiomyosarcoma with a review of literature

1 Department of Pathology, All India Institute of Medical Sciences (AIIMS), Rajkot, Gujarat, India
2 Department of Pathology, Government Medical College, Haldwani, Uttarakhand, India
3 Department of Surgical Oncology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
4 Department of Radiodiagnosis, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India

Correspondence Address:
Tarang Patel,
5,Vaibhav Bungalows, Ghuma, PO Bopal, Ahmedabad-380058, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpm.ijpm_577_21

Uterine leiomyosarcoma (ULMS) is a rare malignancy arising from the myometrial smooth muscle wall, and cardiac metastases are extremely rare. Metastasis to the heart is a very unusual finding, and atrial metastasis is even rarer. Here, we report a case of a 45 year old woman who presented with dyspnea and pleural effusion and had a significant history of hysterectomy done for ULMS. Magnetic resonance imaging revealed a left atrial mass, which was resected and revealed to be a metastasis of leiomyosarcoma on histopathology and immunohistochemistry. Metastatic ULMS may rarely present as a left atrial mass with acute clinical presentation. Detailed clinical history and accurate diagnosis are vital for further management.

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