Indian Journal of Pathology and Microbiology
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Year : 2023  |  Volume : 66  |  Issue : 2  |  Page : 411-414

A retrospective clinicopathological analysis of rhino-orbital mucormycosis in second wave of COVID-19

Department of Pathology, Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India

Correspondence Address:
Brijesh Thakur
Department of Pathology, SGRRIM&HS, Patel Nagar, Dehradun - 248001, Uttarakhand
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpm.ijpm_732_21

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Background: During the present surge of COVID-19 positive cases, concurrent multifold increase in the incidence of mucormycosis cases has resulted into significant morbidity and mortality. We retrospectively evaluated the clinicopathological features along with microbiological examination findings in histologically diagnosed cases of rhino-orbital mucormycosis. Material and Methods: All the H and E and special stained slides of included mucormycosis cases were retrieved from the records and were evaluated with microbiological findings including screening KOH mount examination and culture results. Results: Out of 16 cases with available details, 10 cases had the previous history of diabetes mellitus. The most frequent single site of involvement was maxillary sinus (7/25) followed by nasal cavity, orbit, ethmoid and sphenoid sinuses. While comparing the histological diagnosis with KOH mount findings and culture results, 15 cases revealed consistent results. Conclusion: A high clinical suspicion, monitoring, early diagnosis, and timely management can improve the morbidity and mortality of this life-threatening complication.

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