Indian Journal of Pathology and Microbiology
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Year : 2023  |  Volume : 66  |  Issue : 2  |  Page : 396-399

Biphenotypic sinonasal sarcoma—A recently described entity with many mimics: A case report

1 Department of Pathology, Yashoda Hospital, Hyderabad, Telangana, India
2 ENT Surgery, Yashoda Hospital, Hyderabad, Telangana, India
3 Neuro Surgery, Yashoda Hospital, Hyderabad, Telangana, India

Correspondence Address:
Abhijeet Ingle
Department of Lab Medicine, Yashoda Hospital, Nalagonda X Roads, Malakpet, Hyderabad - 500036, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpm.ijpm_208_21

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Biphenotypic sinonasal sarcoma (BSNS) is a recently described, low-grade, slow-growing sarcoma with neural and myogenic features with exclusive location in sinonasal track and characteristic PAX3- MAML3 gene fusion. Differentiating this tumor from its commoner mimics needs knowledge of this entity to avoid over treatment. This tumor has unique morphology, clinical course, and genetics. We report this in a 47-year-old female who was diagnosed with such a rare, solitary fibrous tumor—hemangiopericytoma (HPC-SFT) on limited initial biopsy. On subsequent excision, typical morphology and immunohistochemistry helped to clinch the diagnosis.

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