Indian Journal of Pathology and Microbiology
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Year : 2022  |  Volume : 65  |  Issue : 3  |  Page : 683-685

IgG4 related sclerosing encapsulating peritonitis with cocoon formation: An unusual and undescribed presentation

1 Department of Histopathology, Sir Gangaram Hospital, New Delhi, India
2 Department of Surgical Gastroenterology and Liver Transplantation, Sir Gangaram Hospital, New Delhi, India

Correspondence Address:
Seema Rao
Department of Histopathology, Sir Gangaram Hospital, New Delhi - 110 060
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpm.ijpm_637_21

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IgG4-related sclerosing mesenteritis is a rare disease of mesentery of an unknown etiology which shows a constellation of histopathologic findings of lymphoplasmacytic inflammation with IgG4-positive plasma cells and marked fibrosis. This chronic inflammatory condition of mesentery forming an abdominal cocoon has never been described before to the best of our knowledge. Here, we report a patient with a history of subacute small bowel obstruction who was found to have an intra-abdominal encapsulating mass in the right iliac fossa and was finally diagnosed as IgG4-related sclerosing encapsulating peritonitis (abdominal cocoon) based on peroperative findings, histology and immunohistochemistry.

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