Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2020  |  Volume : 63  |  Issue : 5  |  Page : 50-52

Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report


1 Department of Pathology, Jiujiang University Clinical Medical College, Jiujiang, China
2 Department of Neurology, Jiujiang University Clinical Medical College, Jiujiang, China

Correspondence Address:
Lin Cheng
Department of Neurology, Jiujiang University Clinical Medical College, Jiujiang 332000
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJPM.IJPM_427_18

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Malignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and magnetic resonance imaging exhibited a cystic mass measuring 8.7 cm × 7.0 cm × 6.7 cm. Immunohistochemical staining showed that the epithelial components were positive for CK8/18 and cytokeratin AE1/AE3; the atypical stromal cells were positive for CD34 and vimentin. Histological analysis resulted in a diagnosis of malignant phyllodes tumor of the prostate. Radical surgery was the treatment of choice. However, tumor recurrence was identified 6 months after the surgery, and the patient died 10 months after the surgery.


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