Indian Journal of Pathology and Microbiology
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  Table of Contents    
Year : 2016  |  Volume : 59  |  Issue : 3  |  Page : 269-270
From Editor's desk

Editor-in-Chief, IJPM, Professor and Head, Department of Pathology, MLN Medical College, Allahabad, Uttar Pradesh, India

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Date of Web Publication10-Aug-2016

How to cite this article:
Misra V. From Editor's desk. Indian J Pathol Microbiol 2016;59:269-70

How to cite this URL:
Misra V. From Editor's desk. Indian J Pathol Microbiol [serial online] 2016 [cited 2022 Aug 11];59:269-70. Available from: https://www.ijpmonline.org/text.asp?2016/59/3/269/188128

Dear Readers,

Greetings for forthcoming festive season of Navratri, Dussehra, and Deepawali. A compilation of research articles covering the various aspects of lesions with infective to neoplastic etiology is being presented here. I am thankful to the authors who have submitted their good research work to the journal for publication. I would also like to take this opportunity to thank the members of the editorial board, international advisors, and reviewers for their untiring efforts in reviewing and correcting the manuscripts. Over the years, the journal has risen to great heights and has come to be widely known across the globe. The journal's impact factor has risen to 0.522 in 2015 as compared to 0.422 in 2014.

Tuberculosis (TB) was initially considered to be a disease of developing countries but with an increase in acquired immunodeficiency it has emerged in developed countries also and about one-third of the world's population, with ~9 million new cases being reported every year.[1] While lung is the primary target of TB, it can also manifest to other organs as an extrapulmonary disease in ~10% of all TB cases. Cutaneous TB (CTB), TB of the skin, is the least common form of extrapulmonary TB, comprising only ~2% of all extrapulmonary tubercular manifestations.[2]

Most diagnostic methods have lower specificity and sensitivity rates for cutaneous presentation as compared to the pulmonary and other extrapulmonary forms. Diagnosis of CTB is challenging because atypical clinical presentation often simulates other inflammatory and neoplastic conditions, which are not uncommon, and may overlap the histological features of CTB.[3] Therefore, multiple techniques need to be performed so that the sum of positive elements can create the basis for CTB.

Afsar and Afsar in their study have evaluated the efficacy of different diagnostic method in cases of CTB.[4] The discussion on the interesting topic has been further improved by the guest editorial written by Ling-Juan, a Dermatologist from, School of Medicine, University of California, San Diego, California, USA.[5]

The human immunodeficiency virus infection and the acquired immunodeficiency syndrome can be complicated by a variety of abnormalities that predominantly consist of lymph nodes, gastrointestinal tract, and other neoplastic lesions. Changes in endocrinal glands have not been discussed frequently. Lanjewar et al. in their autopsy series have described the lesion of the thyroid, in details.[6] They have found that both infective and neoplastic pathology may affect the thyroid in patients with AIDS.

Immunofluorescence (IF) on frozen sections has been considered to be the gold standard for evaluation of kidney biopsy specimens. Therefore, it becomes difficult to make a final diagnosis at many small centers either due to lack of special microscope or costly reagents. Immunohistochemistry (IHC) method can also be used for this purpose with advantages of being applicable on paraffin embedded tissue, providing permanent sections, and not requiring a specialized microscope for interpretation. Shubham et al. have compared the two methods in their study and found that IHC is, with few exceptions, equal to IF for the detection of immunoglobulins. Standardized immunoperoxidase method on the paraffin embedded, formalin-fixed needle kidney biopsies could successfully replace the IF method in the diagnosis of glomerulonephritis.[7]

Besides these, there are other good articles dealing with various new markers in neoplastic lesions such as astrocytoma, uterine smooth muscle tumors, and leukemia along with interesting case reports. I hope all these articles will be of interest to our readers and help them in enhancing their knowledge.

I once again request all the senior members to contribute review articles in their field of expertise and also to new columns such as a quiz, clinicopathological conference, or “How I do it” for the benefit of our budding pathologist. Younger members are advised to take care of plagiarism and follow the instructions of the journal while preparing the manuscript.

With best wishes!

   References Top

Manych M. Tuberculosis – Information report DZK 2015. Pneumologie 2015;69:449.  Back to cited text no. 1
van Zyl L, du Plessis J, Viljoen J. Cutaneous tuberculosis overview and current treatment regimens. Tuberculosis (Edinb) 2015;95:629-38.  Back to cited text no. 2
Santos JB, Figueiredo AR, Ferraz CE, Oliveira MH, Silva PG, Medeiros VL. Cutaneous tuberculosis: Diagnosis, histopathology and treatment – Part II. An Bras Dermatol 2014;89:545-55.  Back to cited text no. 3
Afsar I, Afsar FS. Evaluation of laboratory diagnosis for cutaneous tuberculosis combination of laboratory diagnostic tests for cutaneous tuberculosis 2016;59:275-9.  Back to cited text no. 4
Ling-Juan Z. Combination of laboratory diagnostic tests for cutaneous tuberculosis pathology of thyroid in acquired immunodeficiency syndrome 2016;59:271-2.  Back to cited text no. 5
Lanjewar DN, Ramraje SN, Lanjewar SD. Pathology of thyroid in acquired immunodeficiency syndrome 2016;59:280-5.  Back to cited text no. 6
Shubham S, Bhardwaj M, Mahapatra HS. Comparative evaluation of immunoperoxidase versus immunofluorescent techniques in interpretation of kidney biopsies 2016;59:308-12.  Back to cited text no. 7

Correspondence Address:
Vatsala Misra
Editor-in-Chief, IJPM, Professor and Head, Department of Pathology, MLN Medical College, Allahabad, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.188128

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