Indian Journal of Pathology and Microbiology
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Year : 2015  |  Volume : 58  |  Issue : 4  |  Page : 483-486

Extensive intestinal metaplasia of renal pelvis: Report of a case and literature review

Department of Pathology, Bhopal Memorial Hospital and Research Centre, Bhopal, Madhya Pradesh, India

Correspondence Address:
Dr. Hanni V Gulwani
Department of Pathology, B-19, Type II Doctor Quarters, Bhopal Memorial Hospital and Research Centre Campus, Raisen Bypass Road, Bhopal - 462 038, Madhya Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.168890

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Transformation of the urothelium to the intestinal type of epithelium is rare in the pelvis with very few cases reported in the literature. The present study reports extensive intestinal metaplasia of the pelvi-calyceal system without residual urothelium in a 35-years-old woman with a 2 years history of renal calculi. Right - sided Nephrectomy was undertaken. Immunohistochemistry of the metaplastic epithelium revealed positive expression of CK20, low Ki-67 index and negative expression of p53. In this patient long standing metaplastic changes did not progress to adenocarcinoma which indicates that extensive intestinal metaplasia is not always associated with malignancy.

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