Indian Journal of Pathology and Microbiology
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Year : 2015  |  Volume : 58  |  Issue : 3  |  Page : 381-383

Early onset mixed cryoglobulinemia in hepatitis C

Department of Biochemistry, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi, India

Correspondence Address:
Dr. Kritika Krishnamurthy
Department of Biochemistry, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi - 110002
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Source of Support: Department of Biochemistry, Maulana Azad medical College, Conflict of Interest: None

DOI: 10.4103/0377-4929.162914

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Cryoglobulinemia is one of the most common forms of extrahepatic manifestation of chronic hepatitis infection. The phenomenon is generally seen after several years of chronicity predominantly in the female population resulting in arthralgias, purpuras, and other symptoms, due to vasculitis. Here we present a case of incomplete mixed cryoglobulinemia Type III (as per Brouet's classification) in a young boy aged 13 years who presented with an unusual symptom of pruritus. Diagnosis was confirmed by cryoprecipitation test followed by immunofixation. We aim to highlight the difficulty in diagnosis of this rare case/presentation, important investigation pitfalls and how to avoid them.

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