Indian Journal of Pathology and Microbiology
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Year : 2015  |  Volume : 58  |  Issue : 3  |  Page : 368-370

Psammomatous melanotic schwannoma as a component of Carney complex

1 Department of Histopathology, SRM Institute for Medical Sciences, Chennai, Tamil Nadu, India
2 Department of Neurosciences, SRM Institute for Medical Sciences, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Salapathi Shanmugam
Department of Histopathology, SRM Institute for Medical Sciences, Chennai, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.162903

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Melanotic schwannoma is a rare form of pigmented neural tumor commonly arising from the posterior spinal nerves and ganglia. Two variants have been described, psammomatous and nonpsammomatous. 50% of psammomatous tumors are associated with Carney complex. The biologic behavior of the tumor is difficult to predict and slightly over 10% of the tumors follow malignant course. We present a case of psammomatous melanotic schwannoma as part of Carney complex in a 67-year-old male. Clinical examination revealed oral mucosal and abdominal skin pigmentation. Magnetic resonance imaging showed an intradural extramedullary lesion at D8-D12 level. Intraoperative squash smear study showed sheets of spindle cells with abundant intracytoplasmic melanin pigmentation and few psammoma bodies. Based on clinical, radiologic, and histopathological findings with immunohistochemistry correlation a final diagnosis of psammomatous melanotic schwannoma was rendered.

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