CASE REPORT |
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Year : 2013 | Volume
: 56
| Issue : 4 | Page : 446-448 |
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T-lineage acute lymphoblastic leukemia and parvovirus infection in a child with neurofibromastosis-1
Pallavi Agarwal1, Shano Naseem2, Neelam Varma2, RK Marwaha3
1 Department of Pathology, PGIMER, Chandigarh, India 2 Department of Hematology, PGIMER, Chandigarh, India 3 Department of Pediatrics, PGIMER, Chandigarh, India
Correspondence Address:
Shano Naseem Department of Hematology, PGIMER, Chandigarh - 160 012 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0377-4929.125366
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Neurofibromatosis (NF-1) patients have an increased risk of developing malignancies most commonly rhabdomyosarcomas, optic gliomas, brain tumors and non-lymphocytic leukemias. Acute lymphoblastic leukemia (ALL) has been infrequently reported in association with NF-1. We describe a rare association of NF-1, T-lineage ALL and parvovirus infection in a 12-year-old child. In addition, it is also to emphasize that a high index of suspicion should be kept for parvovirus B19 infection as a cause of bicytopenia/pancytopenia in ALL patients following induction chemotherapy. |
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