Indian Journal of Pathology and Microbiology
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Year : 2009  |  Volume : 52  |  Issue : 2  |  Page : 260-262

Hemophagocytic syndrome: A cause for fatal outcome in tuberculosis

Department of Pathology, Government Medical College, Nagpur, India

Correspondence Address:
Anupama P Gupta
Flat No. 203, Shyam Dham, C.A.Road, Near Ambedkar Square, Babulban, Nagpur - 440 008
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.48939

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Hemophagocytic syndrome is rare syndrome characterized by unregulated proliferation and activation of macrophages and phagocytosis of the platelet, erythrocytes, lymphocytes and their hematopoietic precursors in the bone marrow, resulting in cytopenias. It is associated with stimuli-like infections, malignancies and immunocompromised states. We present here a case of generalized lymphadenopathy, hepatosplenomegaly and progressive cytopenias in a 17-year-old male.

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