Indian Journal of Pathology and Microbiology
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Year : 2009  |  Volume : 52  |  Issue : 1  |  Page : 94-96

Bilateral benign non functional struma ovarii with Pseudo-Meigs' syndrome

1 Department of Pathology, Command Hospital (EC) Alipore, Kolkata 700 027, India
2 Department of Obstetrics and Gynecology, Command Hospital (EC) Alipore, Kolkata 700 027, India
3 Department of Endocrinology, Command Hospital (EC) Alipore, Kolkata 700 027, India

Correspondence Address:
Vandana Rana
Department of Pathology, Command Hospital (EC), Alipore, Kolkata - 700027
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.44978

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Bilateral presentation of benign Struma ovarii is rare and has not been reported frequently in published literature. A 70-year-old postmenopausal female presented with progressive ascites, bilateral pleural effusion and elevated CA-125 levels. The contrast-enhanced computed tomography (CECT) of the abdomen and pelvis revealed a heterogenous mass in the left adnexa. These findings were suspicious for an ovarian malignancy. After surgery the diagnosis of non functional, bilateral benign Struma ovarii was made. Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs' syndrome) in 5% of cases. The combination of struma ovarii and elevated CA-125 levels has been reported infrequently. This is a rare case of bilateral benign struma ovarii associated with Pseudo-Meigs' syndrome and elevated CA-125 levels. Surgical excision of the ovarian masses induced immediate resolution of the ascites and pleural effusion and a reduction of the serum CA-125 level.

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