Indian Journal of Pathology and Microbiology
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Year : 2008  |  Volume : 51  |  Issue : 4  |  Page : 507-508

Mucin-producing signet ring cell adenoma of the thyroid

Department of Histopathology, Sir Ganga Ram Hospital, New Delhi 110 060, India

Correspondence Address:
Hanni Gulwani
Shri V.T.Gulwani, 553/151/5, Adarsh Nagar, Alambagh, Lucknow 226 005
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.43742

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Signet ring cell adenoma of the thyroid, though rare, is well documented. This change is chiefly due to intracellular accumulation of thyroglobulin that appears mucinous. Awareness of this entity is important as it may closely simulate a metastatic mucin-secreting signet ring cell carcinoma. Although the mucinous material in signet ring cells has been reported to stain positive with thyroglobulin, in some cases it may not be so. We herein describe a rare case of a 46-year-old man who was hypothyroid and the mass removed from the thyroid showed a mucin-producing signet ring cell adenoma of the thyroid.

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