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Indian Journal of Pathology and Microbiology
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Year : 2007  |  Volume : 50  |  Issue : 4  |  Page : 782-4

Ganglioneuroma of the adrenal gland : a rare case.


Department of Pathology, All India Institute of Medical Sciences, New Delhi

Correspondence Address:
R Gupta
Department of Pathology, All India Institute of Medical Sciences, New Delhi

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Source of Support: None, Conflict of Interest: None


PMID: 18306553

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Ganglioneuromas, which are benign tumors of sympathetic nervous system, are rare to arise in adrenal gland. They are usually clinically silent and detected during work-up for other unrelated conditions. Currently, histopathology is the only tool to diagnose ganglioneuroma and to differentiate it from ganglioneuroblastoma and neuroblastoma. We discuss the case of a 40-year-old female found to have a right adrenal mass during investigation of dull ache in right upper abdomen. Clinico-radiological assessment was non-confirmatory on the nature of the mass, and excision was done. Histological examination showed the mass to be a ganglioneuroma arising in the adrenal gland. In conclusion, ganglioneuroma occurs rarely in adrenal gland and pre-operative diagnosis is difficult since the symptoms are usually non-specific. Histological examination is the mainstay of diagnosis and should be thorough to exclude neuroblastomatous foci, portending a worse outcome.


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