Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 773
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
Year : 2007  |  Volume : 50  |  Issue : 3  |  Page : 489-92

Immunohistochemical study of the expression of HER-2/neu oncogene in ovarian lesions.

Department of Pathology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana

Correspondence Address:
N Marwah
Department of Pathology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 17883115

Rights and PermissionsRights and Permissions

To evaluate the expression of HER-2/neu in various ovarian lesions, 75 cases of ovarian tissues (25 cases of benign lesions and 50 cases of carcinoma) were studied in the department of pathology, Pt. B.D. Sharma PGIMS, Rohtak. Besides conventional H&E staining, representative sections were processed for immunohistochemical staining for HER-2/neu detection. Two (8%) of benign cases were 1+ positive and 19 (38.0%) of malignant lesions were positive for HER-2/neu staining with intensity 1+/2+ in 16 cases (32.0%), 3+ in 2 cases (4%) and 4+ in 1 case (2%). It was observed that HER-2/neu expression was significantly associated with high grade ovarian tumours, however intensity of positivity did not correlate with the grade of tumour.

[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal