Indian Journal of Pathology and Microbiology
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Year : 2007  |  Volume : 50  |  Issue : 1  |  Page : 63-5

Pseudoglandular pattern of basaloid cells in pilomatrixoma in the needle aspiration cytology : a case report.

Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry

Correspondence Address:
N Siddaraju
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry

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Source of Support: None, Conflict of Interest: None

PMID: 17474263

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A varied cytomorphology of pilomatrixoma often results in diagnostic dilemma. Here, we report a case of pilomatrixoma that presented with prominent gland like arrangement of basaloid cells on cytologic smears causing diagnostic problem. Clinical diagnosis in the present case was cervical lymphadenitis and the cytologic smears showed a strikingly varied morphology with few loose clusters of basaloid cells exhibiting pseudoglandular pattern. A possibility of metastatic carcinoma was considered. However, following histopathologic diagnosis of pilomatrixoma, when cytologic smears were reviewed, it was realized that the ghost cells were overlooked as anucleate squames. Our case highlights the importance of careful clinical and cytologic interpretation of pilomatrixoma. Awareness of the cytomorphologic characteristics of ghost cells and their identification in cytologic smears is highly criticalfor an accurate diagnosis. A prominent basaloid cell component of pilomatrixoma with a pseudoglandular pattern, which has not been described earlier, may easily lead to a false positive diagnosis.

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