Indian Journal of Pathology and Microbiology
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Year : 2006  |  Volume : 49  |  Issue : 4  |  Page : 557-9

Primary amyloidosis presenting as intrahepatic cholestasis.

Department of Medicine, Nil Ratan Sircar Medical College, Kolkata

Correspondence Address:
Sanjay K Bandyopadhyay
Department of Medicine, Nil Ratan Sircar Medical College, Kolkata

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Source of Support: None, Conflict of Interest: None

PMID: 17183853

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Hepatic involvement in primary amyloidosis is not rare but is often clinically silent. A mild elevation of the serum alkaline phosphatase level and hepatomegaly are the most common findings. We report a case of primary amyloidosis in an adult male presenting with intrahepatic cholestasis where viral, drug, alcohol, and autoimmune etiologies were all excluded and the definite diagnosis was established by liver biopsy with Congo red staining. Subsequently the patient was found to have monoclonal light chain disorder.

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