Indian Journal of Pathology and Microbiology
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Year : 2006  |  Volume : 49  |  Issue : 2  |  Page : 283-5

Undifferentiated carcinoma of the submandibular salivary gland with fulminant clinical course : a case report.

Department of Oral Pathology, Govt. Dental College, Trivandrum, Kerala

Correspondence Address:
R Rajendran
Department of Oral Pathology, Govt. Dental College, Trivandrum, Kerala

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Source of Support: None, Conflict of Interest: None

PMID: 16933743

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Undifferentiated carcinoma of salivary glands is too poorly differentiated to be classified as any of the specific group of carcinomas. This is a rare disease, the incidence of which is rather low-to-very low in the Indian subcontinent. The tumor can assume an aggressive clinical behavior characterized by disseminated metastases. The prognosis is rated as dismal; as evidenced by this clinical report of a tumor in the submandibular salivary gland with synchronous metastases to the skull bones and in to the intracranial fossa. The putative relationship of the tumor to Epstein-Barr virus (EBV) infection is discussed.

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