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| Year : 2006 | Volume
: 49
| Issue : 1 | Page : 37-9 |
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Anti Kell allo-antibody in a thalassaemic.
B Thakral, K Saluja, Ratti Ram Sharma, N Marwaha, RK Marwaha
Department of Transfusion Medicine and Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh
Correspondence Address:
B Thakral
Department of Transfusion Medicine and Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 16625974 
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We describe a case of incidental detection of anti Kell antibody in a child with transfusion dependent thalassaemia. Kell antibody detection may be missed by routine indirect antiglobulin test (IAT) crossmatch procedure because of low prevalence of Kell antigen in the general population. A false negative result can be avoided by using sensitive cross matching techniques and screening cells representing antigens in homozygous state, against all clinically significant antibodies. A transfusion alert card describing the nature of antibody and future transfusion policy should be given to such allo-immunized patients. |
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