Indian Journal of Pathology and Microbiology
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Year : 2006  |  Volume : 49  |  Issue : 1  |  Page : 29-31

Inappropriate platelet transfusion in a patient with ethylenediamine tetra- acetic acid (EDTA)--induced pseudothrombocytopenia.

Department of Pathology, Christian Medical College & Hospital, Ludhiana, Punjab

Correspondence Address:
N Kakkar
Department of Pathology, Christian Medical College & Hospital, Ludhiana, Punjab

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Source of Support: None, Conflict of Interest: None

PMID: 16625970

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Automated platelet counts in the laboratory may be fictitiously low at times and require manual confirmation. Ethylenediaminetetra-acetic acid (EDTA) in few patients and healthy individuals can induce platelet aggregation, giving rise to a spuriously low automated platelet count. This phenomenon which occurs due to the presence of IgG antibodies, if unrecognized, can result in incorrect diagnosis and consequent inappropriate treatment. We present a patient who received inappropriate platelet transfusion as a result of EDTA induced spurious thrombocytopenia.

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