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Indian Journal of Pathology and Microbiology
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Year : 2001  |  Volume : 44  |  Issue : 3  |  Page : 257-9

Prognostic significance of apoptosis in squamous cell carcinoma of oral cavity with special reference to TNM stage, histological grade and survival.


Department of Pathology, Maulana Azad Medical College, New Delhi, India

Correspondence Address:
A K Mandal
Department of Pathology, Maulana Azad Medical College, New Delhi, India

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Source of Support: None, Conflict of Interest: None


PMID: 12024908

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Apoptotic count was assessed in 38 cases of squamous cell carcinoma of oral cavity by light microscopy and correlated with TNM stage, histological grade and survival. A direct correlation with the TNM stage (p = 0.0166) and an inverse correlation with the histological grade (p = 0.03) was found, however no correlation was found with the survival. Apoptotic count was significantly different between well and moderately differentiated carcinoma (p = 0.347) and well and poorly differentiated carcinoma (p = 0.0190). Thus apoptotic count may have prognostic value particularly in combination with staging and histological grade.


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