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| Year : 2001 | Volume
: 44
| Issue : 2 | Page : 117-21 |
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Study of anticardiolipin antibodies in repeated abortions--an institutional experience.
J J Sheth, F J Sheth
Endocrine Unit, Dr. Shah's Pathology Laboratory, 1st Floor, Medicare Centre, B/H M.J. Library, Ellisbridge, Ahmedabad
Correspondence Address:
J J Sheth
Endocrine Unit, Dr. Shah's Pathology Laboratory, 1st Floor, Medicare Centre, B/H M.J. Library, Ellisbridge, Ahmedabad
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 11883124 
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A cohort of 178 pregnant women with a history of first or second trimester abortions (2 or more) were the base of present study. In all, other causes of abortion were ruled out except for anti-phospholipid syndrome. Anti-Cardiolipin antibody (ACA) (IgG & IgM) was estimated in the sera samples of all women. Out of 178 women, any one or both immunoglobulins were above the cut off range (> 15.0 units) in 47 (26.4%) while both immunoglobulins were normal in 131 (73.59%) women. Both immunoglobulins were present in only 0.5% women. ACA-IgG alone was present in 11.79% while ACA-IgM alone was present in 14.04% women. We observe from present study that ACA is a major cause of recurrent fetal loss & many pregnancies can be saved if diagnosed & treated adequately. |
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