Indian Journal of Pathology and Microbiology
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Year : 1999  |  Volume : 42  |  Issue : 4  |  Page : 405-9

Detection of mycobacterial antigen in circulating immune complexes in patients with childhood tuberculosis.

Department of Microbiology, Safdarjang Hospital, New Delhi

Correspondence Address:
L Srivastava
Department of Microbiology, Safdarjang Hospital, New Delhi

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Source of Support: None, Conflict of Interest: None

PMID: 11127369

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The presence of both components (antigen and antibody) in circulating immune complexes (CIC) were detected in tuberculosis in children. Fifty two patients with pulmonary and extrapulmonary tuberculosis showed the presence of either components or both. CIC--antigen was present in 92.3% (48/52) and CIC antibody in 88.96% (46,52). Out of these 52 patients, 20 were proved cases, CIC antigen (ag) and CIC--antibody (ab) were present in 100% (20/20). In the control group both CIC-ag and CIC-ab and CIC = ab can be taken as an additional marker in diagnosis of tuberculosis.

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