Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 2409
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
Year : 1998  |  Volume : 41  |  Issue : 3  |  Page : 337-42

Cellular DNA contact and its correlation with histopathological prognostic parameters in carcinoma of the breast.

Department of Pathology, Banaras Hindu University, Varanasi

Correspondence Address:
S Chaturvedi
Department of Pathology, Banaras Hindu University, Varanasi

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 9805857

Rights and PermissionsRights and Permissions

Present study has given an insight in to the value of the DNA in relation to other morphometrics. Breast cancer shows variability in clinical course in the same clinical stage. Cellular DNA content is an important prognostic parameter. Tumour tissue DNA content is correlated with known histopathological prognostic feature assessing its significance as prognostic parameter in 25 cases of carcinoma breast. The findings showed that cellular DNA content ranged between 1.5-5.08 ug/mg in cancer breast tissue with an average of 2.54 ug/mg as compared to an average of 1.34 ug/mg in normal breast tissue. The DNA content was higher in combined pattern, in poorly differentiated duct carcinoma and in patients with positive lymph node metastasis. No consistent relationship could be seen between cellular DNA and desmoplasia and lymphoreticular response in and around tumour.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded25    
    Comments [Add]    

Recommend this journal