Indian Journal of Pathology and Microbiology
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Year : 1998  |  Volume : 41  |  Issue : 1  |  Page : 23-6

C-reactive protein and buffy coat smear in early diagnosis of childhood septicemia.

Department of Microbiology, L.T.M.M.C., Sion, Bombay

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A De
Department of Microbiology, L.T.M.M.C., Sion, Bombay

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Source of Support: None, Conflict of Interest: None

PMID: 9581072

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Out of 200 cases of septicemia in children (age group 0-14 years), 111 had positive C-Reactive Protein (CRP > 12 mg/l) and 84 were buffy coat smear positive. Blood culture was positive in 98 cases, with predominant organism being Klebsiella pneumoniae, followed by Staphylococcus aureus. CRP test showed 100% sensitivity and 87.3% specificity, while buffy coat smear showed 76.5% sensitivity and 91.2% specificity. As blood culture reports are not available before 48-72 hours, combination of CRP test and buffy coat smear examination will be very helpful in early diagnosis of childhood septicemia.

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