Indian Journal of Pathology and Microbiology
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Year : 1998  |  Volume : 41  |  Issue : 1  |  Page : 11-4

A, B & H isoantigens in cervical lesions.

Department of Pathology, Moti Lal Nehru Medical College, Allahabad

Correspondence Address:
D Bisht
Department of Pathology, Moti Lal Nehru Medical College, Allahabad

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Source of Support: None, Conflict of Interest: None

PMID: 9581070

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Expression of A, B and H isoantigens in cervical mucosa was demonstrated by specific red cell adherence test in 92 cervical lesions (40 chronic cervicitis, 12 dysplasia and 40 carcinoma cervix). Eighty percent cases of chronic cervicitis showed a moderate reaction. On the contrary, in carcinoma cervix, 75% cases were found to be SRCA negative. In dysplasia, the intensity of red blood cell adherence was found to be directly related to the degree of cellular differentiation. Study of A, B and H isoantigens might help in deciding the prognosis of dysplasia and/or early detection of malignancy.

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