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Indian Journal of Pathology and Microbiology
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Year : 1995  |  Volume : 38  |  Issue : 4  |  Page : 407-11

Phase contrast microscopic evaluation of placental pathology in premature gestation.


Department of Pathology, Medical College and Hospital, Rohtak

Correspondence Address:
S Batra
Department of Pathology, Medical College and Hospital, Rohtak

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Source of Support: None, Conflict of Interest: None


PMID: 9726153

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Numerous representative samples taken from forty placentas immediately after delivery from mothers associated with prematurity (i.e. less than 38 weeks), were semiquantitatively studied by phase contrast microscopy. Twenty placentas delivered from mothers without any antenatal complication served as control. Hypoplasia of the syncytium, stromal edema, ischaemia were prominent findings on phase contrast microscopy in the study group. Increased basement membrane thickening and high villous edema scores observed on light microscopy were statistically significant in prematurity as compared to controls. Observations by phase contrast and light microscopy were found complementary to each other. Phase contrast microscopy provided quicker results without disadvantage of fixation artefact and was found distinctly superior over the conventional histological methods.


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