Indian Journal of Pathology and Microbiology
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Year : 1995  |  Volume : 38  |  Issue : 4  |  Page : 335-9

Serum complement C4 levels during acute malarial infection and post-treatment period.

Department of Microbiology, J. N. Medical College, Aligarh Muslim University

Correspondence Address:
M E Siddique
Department of Microbiology, J. N. Medical College, Aligarh Muslim University

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Source of Support: None, Conflict of Interest: None

PMID: 9726139

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The researches are conducted in adults and children infected with the species P. falciparum and P. vivax. The results indicated that complement C4 level showed a marked fall during the course of acute malaria in both the children and adults infected with both species. A highly significant hypocomplementaemia was recorded (p < 0.01). Children infected with P. falciparum developed acute cerebral malaria, which was associated with marked hypocomplementaemia. A marked rise in C4 level was noticed on 10th day and it was found normal with reference to control, on 20th and 30th day. A considerable reduction in C4 complement was recorded in P. falciparum when compared to P. vivax.

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